Depression (major depressive disorder)

A common mental health condition involving persistent low mood or loss of interest for two weeks or more, with changes in sleep, energy, and concentration.

Category: Conditions

What is depression?

Depression is more than sadness. Core signs are a persistently low mood and losing interest or pleasure in things you normally care about, lasting most of the day for at least two weeks.

Calm illustrative image for the term Depression (major depressive disorder)

Key things to know

Other symptoms include changes in sleep and appetite, low energy, difficulty concentrating, feelings of worthlessness or guilt, and thoughts of death or self-harm.

  • Core signs: low mood or loss of interest, most of the day, for two weeks or more.
  • It affects the body too: sleep, appetite, energy, and concentration all shift.
  • Depression is not weakness or laziness, and "just think positive" is not treatment.
  • Therapy, medication, or both are effective for most people.
  • Thoughts of self-harm need immediate support: Tele-MANAS 14416 (India, free, 24x7).

What helps

Depression is treatable with psychotherapy, medication, or both. If you have thoughts of harming yourself, contact a crisis line immediately. In India, Tele-MANAS is available at 14416, free and 24x7.

How SelfMind can help

SelfMind is an AI companion for everyday mental health support: a private place to talk through what you are feeling, in Hindi, English or Hinglish, at any hour. It is not therapy and not a crisis service; it works alongside professional care, never in place of it. You can try it free, no account needed.

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Related terms

This entry is educational information, not medical advice, a diagnosis, or a treatment plan. For assessment and treatment, consult a qualified mental health professional. If you are in crisis, see our crisis resources. In India, Tele-MANAS is free at 14416, 24x7.